Epidemiology of HBV in Pregnant Women, South West Nigeria

Glory Atilola; Obadara Tomisin; Mayowa Randle; Komolafe O. Isaac; Gbenga Odutolu; Josephine Olomu; Laide Adenuga

doi:10.2991/j.jegh.2018.09.002

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Volume 8, Issue 3-4, December 2018, Pages 115 - 123

Epidemiology of HBV in Pregnant Women, South West Nigeria

Authors

Glory Atilola¹^{, 2}^{, *}, Obadara Tomisin¹, Mayowa Randle¹, Komolafe O. Isaac¹, Gbenga Odutolu³, Josephine Olomu³, Laide Adenuga³

¹Department of Biological Sciences, Redeemers University, Ede, Osun State, Nigeria

²Department of Mathematics and Statistics, Northumbria University, Newcastle Upon Tyne, UK

³Redeemed AIDS Program Action Committee, Nigeria

^* Corresponding author. Email: glory.atilola@northumbria.ac.uk

Corresponding Author

Glory Atilola

Received 30 March 2018, Revised 4 June 2018, Accepted 3 September 2018, Available Online 31 December 2018.

DOI: 10.2991/j.jegh.2018.09.002 How to use a DOI?
Keywords: HBV; Epidemiology; Pregnant women; South-West; Nigeria
Abstract: Hepatitis B virus (HBV) remains a leading cause of chronic hepatitis, maternal complications, and neonatal deaths in sub-Saharan Africa. Pregnant women serve as a major reservoir for the persistence and ongoing transmission of hepatitis B virus and HIV in a generalized heterosexual epidemic. The aim of this study is to assess the epidemiology of Hepatitis B infection among pregnant women in South West-Nigeria. This is a cross-sectional study of 353 pregnant women across 10 health facilities in the region. Results showed that of the 353 pregnant women tested, 37 were positive for the HBV antigen giving a prevalence estimate of 10.5% (95% CI: 7.5%–14.2%). We found significant negative association between odds of HBV infection and knowledge of HBV transmission through sex (OR: 0.30: 95%CI–0.11–0.82) and a positive association with blood transfusion in the past three months (OR: 9.5: 95% CI-1.58–57.14). Findings strongly suggest high endemicity of HBV and the possible implication of blood transfusion as a major route of ongoing HBV transmission among pregnant women in south-western Nigeria. We recommend further study of a prospective design to investigate the possible causal link between blood transfusion and the risk of HBV infection among pregnant women in Nigeria.
Open Access: This is an open access article under the CC BY-NC license (http://creativecommons.org/licences/by-nc/4.0/).

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Journal: Journal of Epidemiology and Global Health
Volume-Issue: 8 - 3-4
Pages: 115 - 123
Publication Date: 2018/12/31
ISSN (Online): 2210-6014
ISSN (Print): 2210-6006
DOI: 10.2991/j.jegh.2018.09.002 How to use a DOI?
Open Access: This is an open access article under the CC BY-NC license (http://creativecommons.org/licences/by-nc/4.0/).

Cite this article

ris enw bib

TY  - JOUR
AU  - Glory Atilola
AU  - Obadara Tomisin
AU  - Mayowa Randle
AU  - Komolafe O. Isaac
AU  - Gbenga Odutolu
AU  - Josephine Olomu
AU  - Laide Adenuga
PY  - 2018
DA  - 2018/12/31
TI  - Epidemiology of HBV in Pregnant Women, South West Nigeria
JO  - Journal of Epidemiology and Global Health
SP  - 115
EP  - 123
VL  - 8
IS  - 3-4
SN  - 2210-6014
UR  - https://doi.org/10.2991/j.jegh.2018.09.002
DO  - 10.2991/j.jegh.2018.09.002
ID  - Atilola2018
ER  -

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